Comparative Genomics

Comparative Genomics

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Di RienzoAnna Di Rienzo

Professor, Department of Human Genetics

Amount of patterns of genetic variation in human populations.

 

drummond-headshot-2012aAllan D. Drummond

Assistant Professor, Department of Biochemistry & Molecular Biology

Spectrum, frequency and consequences of errors in protein synthesis, sensing and response to misfiled proteins.

 

_w1FCOdm Yoav Gilad

Professor, Department of Human Genetics

Understanding gene regulatory processes and elucidating the genetic architecture of human-specific traits including disease.


Jack_Gilbert_(1)Jack Gilbert

Professor, Department of Surgery

I am interested in microbial ecology, especially the metabolic and signaling reactions between bacteria and their environment, and how communities of microorganisms establish in new environments.

 

 

PIXin He

Assistant Professor, Department of Human Genetics

Computational and statistical methods for identification of genes involved in complex diseases and for regulatory genomics.

 

kratsios-headshotPaschalis Kratsios

Assistant Professor, Department of Neurobiology

Locomotion is an ancient behavior displayed by vertebrate and invertebrate animals. Despite anatomical differences in the execution of locomotion between species, locomotion invariably relies on the function of a specialized network of neuronal and muscle cells known as the motor circuit. Motor neurons lie at the heart of this circuit and display remarkable diversity based on anatomy, electrophysiology and molecular composition. Decades of research on motor neuron development and function have set the foundation upon which we intend to build and expand our knowledge on the molecular principles governing motor neuron diversity and motor circuit assembly.

 

kreitman2Martin Kreitman

Professor, Department of Ecology & Evolution

Population genetics; molecular evolution.

 

 

longManyuan Long

Professor, Department of Ecology & Evolution

New gene evolution: the rates and patterns, the impact of new genes on protein networks, the functional and phenotypic effects; species-specific development and developmental evolution; other problems of genome evolution. Drosophila as experimental systems; in silico genomics of animals and plants.

 

IMG_1270Vincent Lynch

Assistant Professor, Department of Human Genetics

Vertebrate developmental evolution and gene regulation

 

McNerneyMeganMegan McNerney

Assistant Professor, Department of Pathology

Our lab studies the genetic abnormalities in myeloid neoplasms, a type of blood cancer. Using a variety of genomic approaches, we determined that a transcription factor gene, CUX1, is deleted in half of patients with poor-risk myeloid neoplasms. We are now determining the function of CUX1 by a combination of in vivo models and functional genomic approaches. The long-term goal is to leverage this information to identify to new treatments for patients with this disease.

 

Moskowitz,Ivan.sm_Ivan Moskowitz

Associate Professor, Department of Pathology

Molecular genetics of cardiovascular development and congenital heart disease.

 

 

Marcelo NobregaMarcelo Nobrega

Assistant Professor, Department of Human Genetics

Genetics of heart development and congenital heart diseases. Genetic engineering of mouse models of human diseases. Genomic organization and gene regulatory architecture. Vertebrate comparative genomics.

 

Novembre,JohnJohn Novembre

Associate Professor, Department of Human Genetics

Computational approaches to study processes that shape human genetic diversity

 

Ober head shot_8-2014_1Carole Ober

Professor, Department of Human Genetics

Complex trait genetics; QTL mapping; asthma; fertility

 

 

price_trevor_1Trevor Price

Professor, Department of Ecology & Evolution

Genetics of speciation, including molecular studies of gene flow, quantitative genetics of sexually selected traits, and comparative analyses using molecular phylogenies.

 

marsha_newMarsha Rosner

Professor, Ben May Department for Cancer Research

Growth factor receptor signaling leading to cell growth, cell differentiation, or cell death.

 

10517Andrey Rzhetsky

Professor, Department of Medicine

Analysis of complex molecular networks for understanding common phenotypes.

schmidt-ott_uUrs Schmidt-Ott

Associate Professor, Department of Organismal Biology & Anatomy

Developmental genetics and evolution of insects.

 

 

13972Barbara Stranger

Assistant Professor, Department of Medicine

Human population genomics, transcriptome variation, disease genetics, evolution

 

 

wu_c_200x193Chung-I Wu

Professor, Department of Ecology & Evolution

Speciation, genomics, evolutionary genetics, molecular population genetics, sexual selection.