Functional Genomics

Functional Genomics


federmartin-copyMartin Feder

Professor, Department of Organismal Biology & Anatomy

Evolutionary and ecological functional genomics, with Hsp70 and other molecular chaperones in Drosophila as a focus.


_w1FCOdm Yoav Gilad

Professor, Department of Human Genetics

Understanding gene regulatory processes and elucidating the genetic architecture of human-specific traits including disease.


Jack_Gilbert_(1)Jack Gilbert

Professor, Department of Surgery

I am interested in microbial ecology, especially the metabolic and signaling reactions between bacteria and their environment, and how communities of microorganisms establish in new environments.


conrad_gilliamConrad Gilliam

Professor, Department of Human Genetics

Our group is generally focused upon identification of genetic determinants of common genetic disorders, with a particular emphasis on neurological and psychiatric genetic disease.



Chuan-He_3Chuan He

Professor, Department of Chemistry

Regulation of gene expression by dynamic and reversible RNA modifications, epigenetic DNA methylation in various biological processes and human diseases.



PIXin He

Assistant Professor, Department of Human Genetics

Computational and statistical methods for identification of genes involved in complex diseases and for regulatory genomics.




Hae Kyung Im

Assistant Professor, Department of Medicine

Development of statistical methods to make sense of large amounts of genomic and other high dimensional data. Current focus is in the integration of GWAS and functional genomics studies and prediction of complex traits to understand the biology of complex traits.


kratsios-headshotPaschalis Kratsios

Assistant Professor, Department of Neurobiology

Locomotion is an ancient behavior displayed by vertebrate and invertebrate animals. Despite anatomical differences in the execution of locomotion between species, locomotion invariably relies on the function of a specialized network of neuronal and muscle cells known as the motor circuit. Motor neurons lie at the heart of this circuit and display remarkable diversity based on anatomy, electrophysiology and molecular composition. Decades of research on motor neuron development and function have set the foundation upon which we intend to build and expand our knowledge on the molecular principles governing motor neuron diversity and motor circuit assembly.


kreitman2Martin Kreitman

Professor, Department of Ecology & Evolution

Population genetics; molecular evolution.



bruce_lahnBruce Lahn

Professor, Department of Human Genetics

Epigenetic mechanisms of cell fate restriction in stem cell differentiation.


longManyuan Long

Professor, Department of Ecology & Evolution

New gene evolution: the rates and patterns, the impact of new genes on protein networks, the functional and phenotypic effects; species-specific development and developmental evolution; other problems of genome evolution. Drosophila as experimental systems; in silico genomics of animals and plants.

IMG_1270Vincent Lynch

Assistant Professor, Department of Human Genetics

Vertebrate developmental evolution and gene regulation


McNerneyMeganMegan McNerney

Assistant Professor, Department of Pathology

Our lab studies the genetic abnormalities in myeloid neoplasms, a type of blood cancer. Using a variety of genomic approaches, we determined that a transcription factor gene, CUX1, is deleted in half of patients with poor-risk myeloid neoplasms. We are now determining the function of CUX1 by a combination of in vivo models and functional genomic approaches. The long-term goal is to leverage this information to identify to new treatments for patients with this disease.


Moskowitz,Ivan.sm_Ivan Moskowitz

Associate Professor, Department of Pathology

Molecular genetics of cardiovascular development and congenital heart disease.



Marcelo NobregaMarcelo Nobrega

Assistant Professor, Department of Human Genetics

Genetics of heart development and congenital heart diseases. Genetic engineering of mouse models of human diseases. Genomic organization and gene regulatory architecture. Vertebrate comparative genomics.


RuthenburgAlexander Ruthenburg

Assistant Professor, Department of Molecular Genetics & Cell Biology

Chromatin biochemistry, biophysics, and chemical biology.


schmidt-ott_uUrs Schmidt-Ott

Associate Professor, Department of Organismal Biology & Anatomy

Developmental genetics and evolution of insects.



13972Barbara Stranger

Assistant Professor, Department of Medicine

Human population genomics, transcriptome variation, disease genetics, evolution