Gene Regulation

Gene Regulation


Crosson_0Sean Crosson

Assistant Professor, Department of Biochemistry & Molecular Biology

Deciphering the structure, function, and topology of microbial signaling systems.


drummond-headshot-2012aAllan D. Drummond

Assistant Professor, Department of Biochemistry & Molecular Biology

Spectrum, frequency and consequences of errors in protein synthesis, sensing and response to misfiled proteins.


Ferguson_ChipEdwin Ferguson

Professor, Department of Molecular Genetics & Cell Biology

Developmental genetics of cell fate specification and stem cell maintenance


_w1FCOdm Yoav Gilad

Professor, Department of Human Genetics

Understanding gene regulatory processes and elucidating the genetic architecture of human-specific traits including disease.



Chuan-He_3Chuan He

Professor, Department of Chemistry

Regulation of gene expression by dynamic and reversible RNA modifications, epigenetic DNA methylation in various biological processes and human diseases.



He TCTong-Chuan He

Associate Professor, Department of Surgery 

Molecular biology of bone and soft tissue tumors; BMP and Wnt signaling in stem cells; Regulation of mesenchymal stem cell differentiation; Cancer microenvironment and bone metastasis; Gene therapy and regenerative medicine.


Ellie HeckscherEllie Heckscher

Assistant Professor, Department of Molecular Genetics & Cell Biology

Development and function of neural circuits in the motor system



ho_rRobert Ho

Professor, Department of Organismal Biology & Anatomy

Pattern formation and early development in the simple vertebrate zebrafish.




Hae Kyung Im

Assistant Professor, Department of Medicine

Development of statistical methods to make sense of large amounts of genomic and other high dimensional data. Current focus is in the integration of GWAS and functional genomics studies and prediction of complex traits to understand the biology of complex traits.



kratsios-headshotPaschalis Kratsios

Assistant Professor, Department of Neurobiology

Locomotion is an ancient behavior displayed by vertebrate and invertebrate animals. Despite anatomical differences in the execution of locomotion between species, locomotion invariably relies on the function of a specialized network of neuronal and muscle cells known as the motor circuit. Motor neurons lie at the heart of this circuit and display remarkable diversity based on anatomy, electrophysiology and molecular composition. Decades of research on motor neuron development and function have set the foundation upon which we intend to build and expand our knowledge on the molecular principles governing motor neuron diversity and motor circuit assembly.


kreitman2Martin Kreitman

Professor, Department of Ecology & Evolution

Population genetics; molecular evolution.



stephen_kronStephen Kron

Professor, Department of Molecular Genetics & Cell Biology

Signal transduction, DNA damage checkpoints, cell cycle control, and epigenetic. Technology for proteomics, drug discovery and systems biology.


bruce_lahnBruce Lahn

Professor, Department of Human Genetics

Epigenetic mechanisms of cell fate restriction in stem cell differentiation.



IMG_1270Vincent Lynch

Assistant Professor, Department of Human Genetics

Vertebrate developmental evolution and gene regulation


McNerneyMeganMegan McNerney

Assistant Professor, Department of Pathology

Our lab studies the genetic abnormalities in myeloid neoplasms, a type of blood cancer. Using a variety of genomic approaches, we determined that a transcription factor gene, CUX1, is deleted in half of patients with poor-risk myeloid neoplasms. We are now determining the function of CUX1 by a combination of in vivo models and functional genomic approaches. The long-term goal is to leverage this information to identify to new treatments for patients with this disease.


Moskowitz,Ivan.sm_Ivan Moskowitz

Associate Professor, Department of Pathology

Molecular genetics of cardiovascular development and congenital heart disease.



Marcelo NobregaMarcelo Nobrega

Assistant Professor, Department of Human Genetics

Genetics of heart development and congenital heart diseases. Genetic engineering of mouse models of human diseases. Genomic organization and gene regulatory architecture. Vertebrate comparative genomics.


Vicky Prince1Victoria Prince

Professor, Department of Organismal Biology & Anatomy

Molecular, cellular, and comparative study of vertebrate axial patterning using the zebrafish model.


rebay_10_06_1Ilaria Rebay

Professor, Ben May Department for Cancer Research

Transcriptional regulatory circuitries in development and disease; Receptor tyrosine kinase signal transduction.



reinitz_john192x246John Reinitz

Professor, Department of Statistics

My laboratory is engaged in a long term project to understand how DNA sequence specifies biological form. We are interested not only in the specification of typical form by a typical genome, but also in the effects of variability. Such variability might take the form of genetic variation in a population or intrinsic fluctuations in an individual. These problems touch on issues central to developmental and evolutionary biology, and efforts to solve them have previously led to the development of new branches of mathematics.


marsha_newMarsha Rosner

Professor, Ben May Department for Cancer Research

Growth factor receptor signaling leading to cell growth, cell differentiation, or cell death.


rothman-denes_luciaLucia Rothman-Denes

Professor, Department of Molecular Genetics & Cell Biology

RNA polymerase structure and function; mechanisms of transcription regulation; host-viral interactions.


rust_bwMichael Rust

Assistant Professor, Department of Molecular Genetics & Cell Biology

Biophysical and biochemical study of the architecture and robustness of biological systems; cyanobacterial circadian clock.


RuthenburgAlexander Ruthenburg

Assistant Professor, Department of Molecular Genetics & Cell Biology

Chromatin biochemistry, biophysics, and chemical biology.




schmidt-ott_uUrs Schmidt-Ott

Associate Professor, Department of Organismal Biology & Anatomy

Developmental genetics and evolution of insects.


Jon-crop2Jonathan Staley

Professor, Department of Cell & Molecular Biology

Pre-mRNA splicing; non-coding RNA function, mechanism, and regulation.