Xuanyao Liu, Ph.D.
My lab is interested in studying the genetic basis of complex traits and diseases by developing statistical methods and analyzing multi-omic data. I am very excited to start my research group here at UChicago because there are opportunities to work with highly motivated graduate students and trainees and collaborate with world-leading experts in statistical genetics and human genetics. My goal as a new faculty is to work closely with my students and trainees and provide ample support for them to succeed in academia and industry.
University of Chicago scientist Chuan He found evidence that RNA itself modulates how DNA is transcribed—using a chemical process that is increasingly apparent to be vital to biology.
A transgenic C.elegans worm, where the motor neurons are labeled with two fluorescent reporters (green and red). Motor neurons are located on the under side of the worm, positioned one after the other, and appear as green and red dots. The top three panels are fluorescent images, and the bottom panel shows the actual animal together with the fluorescently labeled motor neurons.
Adult rhesus macaque monkeys' previous status in their community's social hierarchy has a lingering effect on how their genes behave.
A macrophage (in white) engulfs a cancer cell. When these immune cells respond to infection or tumors, they produce a substance call lactate, which can actually fuel cancer growth.
Software identified the METTL3 gene (left) as a potential "driver gene" for bladder cancer. The closeups below show areas with genetic mutations.