Maanasa Raghavan

Assistant Professor
Research Summary
My group's research interests span questions and applications in multiple fields, including population genetics/genomics, anthropology, archaeology, and medical genetics. The big question driving our research is: ‘How have demographic, cultural, and environmental factors contributed over time to shaping the genetic profiles of present-day human populations?’ In order to address specific research questions embedded within this overarching goal, we use a combined approach that brings together genome-scale data from present-day and ancient humans and their biotic environment, especially domesticates and pathogens. Through the implementation of multiple complementary projects set within the global context, our research will ultimately contribute towards the understanding of the evolutionary mechanisms that underlie adaptations and diseases among human populations.
Population and Evolutionary Genetics, Ancient DNA, Genomics, Human Evolution
  • University of Copenhagen, Denmark, PhD Paleogenomics (ancient DNA) 12/2011
  • University of Oxford, UK, MSc Archaeological Sciences 09/2007
  • University of Toronto, Canada, BSc (Hons) Molecular Biology 06/2006
Biosciences Graduate Program Association
Awards & Honors
  • 2018 - 2023 Neubauer Family Assistant Professors Program University of Chicago
  1. Recommendations for Sustainable Ancient DNA Research in the Global South: Voices From a New Generation of Paleogenomicists. Front Genet. 2022; 13:880170. View in: PubMed

  2. The Articulation of Genomics, Mestizaje, and Indigenous Identities in Chile: A Case Study of the Social Implications of Genomic Research in Light of Current Research Practices. Front Genet. 2022; 13:817318. View in: PubMed

  3. An Ancient Genome from the Indus Valley Civilization. Cell. 2019 10 17; 179(3):586-588. View in: PubMed

  4. DNA evidence of bowhead whale exploitation by Greenlandic Paleo-Inuit 4,000 years ago. Nat Commun. 2016 11 08; 7:13389. View in: PubMed

  5. POPULATION GENETICS. Genomic evidence for the Pleistocene and recent population history of Native Americans. Science. 2015 Aug 21; 349(6250):aab3884. View in: PubMed

  6. Prehistoric genomes reveal the genetic foundation and cost of horse domestication. Proc Natl Acad Sci U S A. 2014 Dec 30; 111(52):E5661-9. View in: PubMed

  7. Ancient genomics. Philos Trans R Soc Lond B Biol Sci. 2015 Jan 19; 370(1660):20130387. View in: PubMed

  8. Two ancient human genomes reveal Polynesian ancestry among the indigenous Botocudos of Brazil. Curr Biol. 2014 Nov 03; 24(21):R1035-7. View in: PubMed

  9. A Selective Sweep on a Deleterious Mutation in CPT1A in Arctic Populations. Am J Hum Genet. 2014 11 06; 95(5):584-589. View in: PubMed

  10. Ancient DNA reveals matrilineal continuity in present-day Poland over the last two millennia. PLoS One. 2014; 9(10):e110839. View in: PubMed

  11. The genetic prehistory of the New World Arctic. Science. 2014 Aug 29; 345(6200):1255832. View in: PubMed

  12. Rodents of the Caribbean: origin and diversification of hutias unravelled by next-generation museomics. Biol Lett. 2014 Jul; 10(7). View in: PubMed

  13. Genomic diversity and admixture differs for Stone-Age Scandinavian foragers and farmers. Science. 2014 May 16; 344(6185):747-50. View in: PubMed

  14. Upper Palaeolithic Siberian genome reveals dual ancestry of Native Americans. Nature. 2014 Jan 02; 505(7481):87-91. View in: PubMed

  15. Recalibrating Equus evolution using the genome sequence of an early Middle Pleistocene horse. Nature. 2013 Jul 04; 499(7456):74-8. View in: PubMed

  16. Mitochondrial phylogenomics of modern and ancient equids. PLoS One. 2013; 8(2):e55950. View in: PubMed

  17. Clovis age Western Stemmed projectile points and human coprolites at the Paisley Caves. Science. 2012 Jul 13; 337(6091):223-8. View in: PubMed

  18. Origins and genetic legacy of Neolithic farmers and hunter-gatherers in Europe. Science. 2012 Apr 27; 336(6080):466-9. View in: PubMed

  19. True single-molecule DNA sequencing of a pleistocene horse bone. Genome Res. 2011 Oct; 21(10):1705-19. View in: PubMed

  20. Ancient human genome sequence of an extinct Palaeo-Eskimo. Nature. 2010 Feb 11; 463(7282):757-62. View in: PubMed

  21. Amino acid delta13C analysis of hair proteins and bone collagen using liquid chromatography/isotope ratio mass spectrometry: paleodietary implications from intra-individual comparisons. Rapid Commun Mass Spectrom. 2010 Mar 15; 24(5):541-8. View in: PubMed

  22. Preservation of cell structures in a medieval infant brain: a paleohistological, paleogenetic, radiological and physico-chemical study. Neuroimage. 2010 Apr 15; 50(3):893-901. View in: PubMed

  23. Examining protein protein interactions using endogenously tagged yeast arrays: the cross-and-capture system. Genome Res. 2007 Dec; 17(12):1774-82. View in: PubMed

  24. Recommendations for Sustainable Ancient DNA Research in the Global South: Voices From a New Generation of Paleogenomicists. Frontiers in Genetics. 2022.::::