We study human genomic factors that control and interact with the microbiome. We utilize high-throughput genomics technologies and employ computational, statistical, machine learning, and population genetic analytical approaches, with the goal of understanding how we interact with our microbial communities, how host-microbe interactions affect human disease, and how the symbiosis between us and our microbiome evolved.
Assembly, stability, and dynamics of the infant gut microbiome are linked to bacterial strains and functions in mother's milk.
Assembly, stability, and dynamics of the infant gut microbiome are linked to bacterial strains and functions in mother's milk. bioRxiv. 2024 Jan 28.
PMID: 38328166
Multi-omic approaches for host-microbiome data integration.
Multi-omic approaches for host-microbiome data integration. Gut Microbes. 2024 Jan-Dec; 16(1):2297860.
PMID: 38166610
Integration of 168,000 samples reveals global patterns of the human gut microbiome.
Integration of 168,000 samples reveals global patterns of the human gut microbiome. bioRxiv. 2023 Oct 11.
PMID: 37873416
Human Cytomegalovirus in breast milk is associated with milk composition, the infant gut microbiome, and infant growth.
Human Cytomegalovirus in breast milk is associated with milk composition, the infant gut microbiome, and infant growth. bioRxiv. 2023 Jul 19.
PMID: 37503212
Microbes with higher metabolic independence are enriched in human gut microbiomes under stress.
Microbes with higher metabolic independence are enriched in human gut microbiomes under stress. bioRxiv. 2023 May 26.
PMID: 37293035
Universal gut microbial relationships in the gut microbiome of wild baboons.
Universal gut microbial relationships in the gut microbiome of wild baboons. Elife. 2023 05 09; 12.
PMID: 37158607
Human milk variation is shaped by maternal genetics and impacts the infant gut microbiome.
Human milk variation is shaped by maternal genetics and impacts the infant gut microbiome. bioRxiv. 2023 Jan 25.
PMID: 36747843
How longitudinal data can contribute to our understanding of host genetic effects on the gut microbiome.
How longitudinal data can contribute to our understanding of host genetic effects on the gut microbiome. Gut Microbes. 2023 Jan-Dec; 15(1):2178797.
PMID: 36794811
Codiversification of gut microbiota with humans.
Codiversification of gut microbiota with humans. Science. 2022 09 16; 377(6612):1328-1332.
PMID: 36108023
Synchrony and idiosyncrasy in the gut microbiome of wild baboons.
Synchrony and idiosyncrasy in the gut microbiome of wild baboons. Nat Ecol Evol. 2022 07; 6(7):955-964.
PMID: 35654895