My research focuses on understanding and uncovering the genetic basis and biological mechanisms of diseases by combining computational genomics, statistical genetics, and human genetics. We are particularly interested in interpreting disease-associated genetic variants with functional genomics, single cell omics and gene regulatory networks. We are also broadly interested in understanding genetic architectures of diseases across populations and improving the portability of genetic prediction.
Harvard School of Public Health
Boston, USA
Postdoc - Statistical Genetics
2017
National University of Singapore
Singapore, Singapore
PHD - Population Genetics
2014
National University of Singapore
Singapore, Singapore
Bachelor of Science - Computational Biology
2010
GBAT: a gene-based association test for robust detection of trans-gene regulation.
GBAT: a gene-based association test for robust detection of trans-gene regulation. Genome Biol. 2020 08 24; 21(1):211.
PMID: 32831138
Trans Effects on Gene Expression Can Drive Omnigenic Inheritance.
Trans Effects on Gene Expression Can Drive Omnigenic Inheritance. Cell. 2019 05 02; 177(4):1022-1034.e6.
PMID: 31051098