We develop quantitative and computational methods and tools to sift through the vast amounts of genomic and other high dimensional data with the goal of making discoveries that can be translated to improve human health.
University of Chicago
Chicago
PhD - Statistics
2005
OmicsPred as a centralized resource for genetic prediction of multi-omic traits.
OmicsPred as a centralized resource for genetic prediction of multi-omic traits. Nat Genet. 2026 Sep 01.
PMID: 42680840
Systematic Integration of genomics with transcriptomics for the Study of Coronary Artery Disease and Subclinical Atherosclerosis.
Systematic Integration of genomics with transcriptomics for the Study of Coronary Artery Disease and Subclinical Atherosclerosis. medRxiv. 2026 Aug 03.
PMID: 42620441
Multi-ancestry modeling improves fine-mapping resolution, protein prediction, and discovery for proteome-wide association studies.
Multi-ancestry modeling improves fine-mapping resolution, protein prediction, and discovery for proteome-wide association studies. medRxiv. 2026 Jul 01.
PMID: 42428118
A pleiotropic EPAS1 enhancer mediating Tibetan adaptation to hypoxia is active in adipocytes.
A pleiotropic EPAS1 enhancer mediating Tibetan adaptation to hypoxia is active in adipocytes. bioRxiv. 2026 Jun 15.
PMID: 42367842
OmicsPred as a centralised resource for genetic prediction of multi-omic traits.
OmicsPred as a centralised resource for genetic prediction of multi-omic traits. medRxiv. 2026 Jun 11.
PMID: 42238397
Multi-ancestry transcriptome prediction with functionally informed variants in TOPMed MESA improves performance of transcriptome-wide association studies.
Multi-ancestry transcriptome prediction with functionally informed variants in TOPMed MESA improves performance of transcriptome-wide association studies. Am J Hum Genet. 2026 Apr 02; 113(4):828-841.
PMID: 41932314
Network pharmacology-based discovery and experimental validation of novel drug repurposing candidates in Alzheimer's Disease.
Network pharmacology-based discovery and experimental validation of novel drug repurposing candidates in Alzheimer's Disease. bioRxiv. 2026 Mar 09.
PMID: 41959283
Multi-trait polygenic scores for COPD and COPD exacerbations implicate druggable proteins.
Multi-trait polygenic scores for COPD and COPD exacerbations implicate druggable proteins. JCI Insight. 2026 04 08; 11(7).
PMID: 41712304
Protocol to perform cell-type-specific transcriptome-wide association study using scPrediXcan framework.
Protocol to perform cell-type-specific transcriptome-wide association study using scPrediXcan framework. STAR Protoc. 2026 Mar 20; 7(1):104306.
PMID: 41689808
A gene-specific variance-control approach corrects polygenicity-driven inflation observed in transcriptome-wide association studies.
A gene-specific variance-control approach corrects polygenicity-driven inflation observed in transcriptome-wide association studies. Am J Hum Genet. 2026 Feb 05; 113(2):276-290.
PMID: 41564881